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Activation of the Aspergillus PacC zinc finger transcription factor requires two proteolytic steps
The Aspergillus PacC transcription factor undergoes proteolytic activation in response to alkaline ambient pH. In acidic environments, the 674 residue translation product adopts a ‘closed’ conformation, protected from activation through intramolecular interactions involving the ≤150 residue C-termin...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2002
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC125927/ https://ncbi.nlm.nih.gov/pubmed/11889040 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/21.6.1350 |
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