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Conserved segments 1A and 2B of the intermediate filament dimer: their atomic structures and role in filament assembly

Intermediate filaments (IFs) are key components of the cytoskeleton in higher eukaryotic cells. The elementary IF ‘building block’ is an elongated coiled-coil dimer consisting of four consecutive α-helical segments. The segments 1A and 2B include highly conserved sequences and are critically involve...

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Udgivet i:EMBO J
Principais autores: Strelkov, Sergei V., Herrmann, Harald, Geisler, Norbert, Wedig, Tatjana, Zimbelmann, Ralf, Aebi, Ueli, Burkhard, Peter
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2002
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Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC125921/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11889032/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/21.6.1255
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