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Conserved segments 1A and 2B of the intermediate filament dimer: their atomic structures and role in filament assembly

Intermediate filaments (IFs) are key components of the cytoskeleton in higher eukaryotic cells. The elementary IF ‘building block’ is an elongated coiled-coil dimer consisting of four consecutive α-helical segments. The segments 1A and 2B include highly conserved sequences and are critically involve...

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Detalhes bibliográficos
Main Authors: Strelkov, Sergei V., Herrmann, Harald, Geisler, Norbert, Wedig, Tatjana, Zimbelmann, Ralf, Aebi, Ueli, Burkhard, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2002
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC125921/
https://ncbi.nlm.nih.gov/pubmed/11889032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/21.6.1255
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