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Cell cycle-dependent regulation of the association between origin recognition proteins and somatic cell chromatin

Previous studies have suggested that cell cycle-dependent changes in the affinity of the origin recognition complex (ORC) for chromatin are involved in regulating initiation of DNA replication. To test this hypothesis, chromatin lacking functional ORCs was isolated from metaphase hamster cells and i...

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Detalhes bibliográficos
Main Authors: Sun, Wei-Hsin, Coleman, Thomas R., DePamphilis, Melvin L.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC125915/
https://ncbi.nlm.nih.gov/pubmed/11889049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/21.6.1437
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