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A genetic screen for improved plasmid segregation reveals a role for Rep20 in the interaction of Plasmodium falciparum chromosomes

Bacterial plasmids introduced into the human malaria parasite Plasmodium falciparum replicate well but are poorly segregated during mitosis. In this paper, we screened a random P.falciparum genomic library in order to identify sequences that overcome this segregation defect. Using this approach, we...

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Detalhes bibliográficos
Main Authors: O’Donnell, Rebecca A., Freitas-Junior, Lúcio H., Preiser, Peter R., Williamson, Donald H., Duraisingh, Manoj, McElwain, Terry F., Scherf, Artur, Cowman, Alan F., Crabb, Brendan S.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2002
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC125903/
https://ncbi.nlm.nih.gov/pubmed/11867551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/21.5.1231
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