A cyclophilin functions in pre-mRNA splicing

We report that the cyclophilin USA-CyP is part of distinct complexes with two spliceosomal proteins and is involved in both steps of pre-mRNA splicing. The splicing factors hPrp18 and hPrp4 have a short region of homology that defines a high affinity binding site for USA-CyP in each protein. USA-CyP...

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Bibliografske podrobnosti

izdano v:	EMBO J
Principais autores:	Horowitz, David S., Lee, Edward J., Mabon, Stephen A., Misteli, Tom
Format:	Artigo
Jezik:	Inglês
Izdano:	Nature Publishing Group 2002
Teme:	Article
Online dostop:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC125845/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11823439/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/21.3.470
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