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A cyclophilin functions in pre-mRNA splicing

We report that the cyclophilin USA-CyP is part of distinct complexes with two spliceosomal proteins and is involved in both steps of pre-mRNA splicing. The splicing factors hPrp18 and hPrp4 have a short region of homology that defines a high affinity binding site for USA-CyP in each protein. USA-CyP...

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Autors principals: Horowitz, David S., Lee, Edward J., Mabon, Stephen A., Misteli, Tom
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2002
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC125845/
https://ncbi.nlm.nih.gov/pubmed/11823439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/21.3.470
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