Cyclin-dependent kinase 5 prevents neuronal apoptosis by negative regulation of c-Jun N-terminal kinase 3

Cyclin-dependent kinase 5 (cdk5) is a serine/threonine kinase activated by associating with its neuron-specific activators p35 and p39. Analysis of cdk5(–/–) and p35(–/–) mice has demonstrated that both cdk5 and p35 are essential for neuronal migration, axon pathfinding and the laminar configuration...

ver descrição completa

Detalhes bibliográficos

Publicado no:	EMBO J
Principais autores:	Li, Bing-Sheng, Zhang, Lei, Takahashi, Satoru, Ma, Wu, Jaffe, Howard, Kulkarni, Ashok B., Pant, Harish C.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Publishing Group 2002
Assuntos:	Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC125822/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11823425/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/21.3.324
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!