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Shy1p is necessary for full expression of mitochondrial COX1 in the yeast model of Leigh’s syndrome
SHY1 codes for a mitochondrial protein required for full expression of cytochrome oxidase (COX) in Saccharomyces cerevisiae. Mutations in the homologous human gene (SURF1) have been reported to cause Leigh’s syndrome, a neurological disease associated with COX deficiency. The function of Shy1p/Surf1...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2002
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC125806/ https://ncbi.nlm.nih.gov/pubmed/11782424 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/21.1.43 |
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