טוען...
A highly selective telomerase inhibitor limiting human cancer cell proliferation
Telomerase, the ribonucleoprotein enzyme maintaining the telomeres of eukaryotic chromosomes, is active in most human cancers and in germline cells but, with few exceptions, not in normal human somatic tissues. Telomere maintenance is essential to the replicative potential of malignant cells and the...
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Main Authors: | , , , , , , , , , , , , , , , , , , , , |
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פורמט: | Artigo |
שפה: | Inglês |
יצא לאור: |
Oxford University Press
2001
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גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC125790/ https://ncbi.nlm.nih.gov/pubmed/11742973 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.24.6958 |
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