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Structure of a two-domain fragment of HIV-1 integrase: implications for domain organization in the intact protein

Retroviral integrase, an essential enzyme for replication of human immunodeficiency virus type-1 (HIV-1) and other retroviruses, contains three structurally distinct domains, an N-terminal domain, the catalytic core and a C-terminal domain. To elucidate their spatial arrangement, we have solved the...

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Bibliografische gegevens
Hoofdauteurs: Wang, Jian-Yong, Ling, Hong, Yang, Wei, Craigie, Robert
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2001
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC125787/
https://ncbi.nlm.nih.gov/pubmed/11743009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.24.7333
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