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Structure of a two-domain fragment of HIV-1 integrase: implications for domain organization in the intact protein
Retroviral integrase, an essential enzyme for replication of human immunodeficiency virus type-1 (HIV-1) and other retroviruses, contains three structurally distinct domains, an N-terminal domain, the catalytic core and a C-terminal domain. To elucidate their spatial arrangement, we have solved the...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2001
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC125787/ https://ncbi.nlm.nih.gov/pubmed/11743009 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.24.7333 |
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