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Origin pairing (‘handcuffing’) as a mode of negative control of P1 plasmid copy number

In one family of bacterial plasmids, multiple initiator binding sites, called iterons, are used for initiation of plasmid replication as well as for the control of plasmid copy number. Iterons can also pair in vitro via the bound initiators. This pairing, called handcuffing, has been suggested to ca...

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Detalhes bibliográficos
Main Authors: Park, Kyusung, Han, Ernest, Paulsson, Johan, Chattoraj, Dhruba K.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC125786/
https://ncbi.nlm.nih.gov/pubmed/11743008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.24.7323
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