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Retroviral oncoprotein Tax induces processing of NF-κB2/p100 in T cells: evidence for the involvement of IKKα

IκB kinase (IKK) is a key mediator of NF-κB activation induced by various immunological signals. In T cells and most other cell types, the primary target of IKK is a labile inhibitor of NF-κB, IκBα, which is responsible for the canonical NF-κB activation. Here, we show that in T cells infected with...

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Detalhes bibliográficos
Main Authors: Xiao, Gutian, Cvijic, Mary Ellen, Fong, Abraham, Harhaj, Edward W., Uhlik, Mark T., Waterfield, Michael, Sun, Shao-Cong
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC125766/
https://ncbi.nlm.nih.gov/pubmed/11726516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.23.6805
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