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Fission yeast Rad50 stimulates sister chromatid recombination and links cohesion with repair

To study the role of Rad50 in the DNA damage response, we cloned and deleted the Schizosaccharo myces pombe RAD50 homologue. The deletion is sensitive to a range of DNA-damaging agents and shows dynamic epistatic interactions with other recombin ation–repair genes. We show that Rad50 is necessary fo...

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Detalles Bibliográficos
Publicado en:EMBO J
Autores principales: Hartsuiker, E., Vaessen, E., Carr, A.M., Kohli, J.
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2001
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC125746/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11726502/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/20.23.6660
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