Fission yeast Rad50 stimulates sister chromatid recombination and links cohesion with repair
To study the role of Rad50 in the DNA damage response, we cloned and deleted the Schizosaccharo myces pombe RAD50 homologue. The deletion is sensitive to a range of DNA-damaging agents and shows dynamic epistatic interactions with other recombin ation–repair genes. We show that Rad50 is necessary fo...
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| Publicado no: | EMBO J |
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| Principais autores: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC125746/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11726502/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/20.23.6660 |
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