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Competing sorting signals guide endolyn along a novel route to lysosomes in MDCK cells

We have examined the trafficking of the mucin-like protein endolyn in transfected, polarized MDCK cells using biochemical approaches and immunofluorescence microscopy. Although endolyn contains a lysosomal targeting motif of the type YXXΦ and was localized primarily to lysosomes at steady state, sig...

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Main Authors: Ihrke, Gudrun, Bruns, Jennifer R., Luzio, J.Paul, Weisz, Ora A.
格式: Artigo
語言:Inglês
出版: Oxford University Press 2001
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC125743/
https://ncbi.nlm.nih.gov/pubmed/11707397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.22.6256
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