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Octacalcium phosphate crystals directly stimulate expression of inducible nitric oxide synthase through p38 and JNK mitogen-activated protein kinases in articular chondrocytes

Basic calcium phosphate (BCP) crystals, including hydroxyapatite, octacalcium phosphate (OCP) and carbonate-apatite, have been associated with severe osteoarthritis and several degenerative arthropathies. Most studies have considered the chondrocyte to be a bystander in the pathogenesis of calcium c...

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Detalhes bibliográficos
Main Authors: Ea, Hang-Korng, Uzan, Benjamin, Rey, Christian, Lioté, Frédéric
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1257419/
https://ncbi.nlm.nih.gov/pubmed/16207333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar1763
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