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Transcriptional feedback control of insulin receptor by dFOXO/FOXO1
The insulin signaling pathway, which is conserved in evolution from flies to humans, evolved to allow a fast response to changes in nutrient availability while keeping glucose concentration constant in serum. Here we show that, both in Drosophila and mammals, insulin receptor (InR) represses its own...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2005
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1257398/ https://ncbi.nlm.nih.gov/pubmed/16230533 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1340505 |
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