Structure of a fast kinesin: implications for ATPase mechanism and interactions with microtubules

We determined the crystal structure of the motor domain of the fast fungal kinesin from Neurospora crassa (NcKin). The structure has several unique features. (i) Loop 11 in the switch 2 region is ordered and enables one to describe the complete nucleotide-binding pocket, including three inter-switch...

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Pubblicato in:	EMBO J
Autori principali:	Song, Y.-H., Marx, A., Müller, J., Woehlke, G., Schliwa, M., Krebs, A., Hoenger, A., Mandelkow, E.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Nature Publishing Group 2001
Soggetti:	Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC125725/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11707393/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/20.22.6213
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