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Purified kinesin promotes vesicle motility and induces active sliding between microtubules in vitro.

We examined the ability of kinesin to support the movement of adrenal medullary chromaffin granules on microtubules in a defined in vitro system. We found that kinesin and ATP are all that is required to support efficient (33% vesicle motility) and rapid (0.4-0.6 micron/s) translocation of secretory...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Urrutia, R, McNiven, M A, Albanesi, J P, Murphy, D B, Kachar, B
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 1991
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Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC52156/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1830666/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.15.6701
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