The structure-specific endonuclease Ercc1–Xpf is required for targeted gene replacement in embryonic stem cells
The Ercc1–Xpf heterodimer, a highly conserved structure-specific endonuclease, functions in multiple DNA repair pathways that are pivotal for maintaining genome stability, including nucleotide excision repair, interstrand crosslink repair and homologous recombination. Ercc1–Xpf incises double-strand...
Sábháilte in:
| Foilsithe in: | EMBO J |
|---|---|
| Príomhchruthaitheoirí: | , , , , , , , , |
| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe / Cruthaithe: |
Nature Publishing Group
2001
|
| Ábhair: | |
| Rochtain ar líne: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC125716/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11707424/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/20.22.6540 |
| Clibeanna: |
Níl clibeanna ann, Bí ar an gcéad duine le clib a chur leis an taifead seo!
|