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The hnRNP A1 protein regulates HIV-1 tat splicing via a novel intron silencer element
The generation of >30 different HIV-1 mRNAs is achieved by alternative splicing of one primary transcript. The removal of the second tat intron is regulated by a combination of a suboptimal 3′ splice site and cis-acting splicing enhancers and silencers. Here we show that hnRNP A1 inhibits splicin...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC125679/ https://ncbi.nlm.nih.gov/pubmed/11598017 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.20.5748 |
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