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Yeast Hct1 recognizes the mitotic cyclin Clb2 and other substrates of the ubiquitin ligase APC

Ubiquitin-mediated proteolysis has emerged as a key mechanism of regulation in eukaryotic cells. During cell division, a multi-subunit ubiquitin ligase termed the anaphase promoting complex (APC) targets critical regulatory proteins such as securin and mitotic cyclins, and thereby triggers chromosom...

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Autors principals: Schwab, Michael, Neutzner, Melanie, Möcker, Doreen, Seufert, Wolfgang
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2001
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC125620/
https://ncbi.nlm.nih.gov/pubmed/11566880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.18.5165
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