Yeast Hct1 recognizes the mitotic cyclin Clb2 and other substrates of the ubiquitin ligase APC

Ubiquitin-mediated proteolysis has emerged as a key mechanism of regulation in eukaryotic cells. During cell division, a multi-subunit ubiquitin ligase termed the anaphase promoting complex (APC) targets critical regulatory proteins such as securin and mitotic cyclins, and thereby triggers chromosom...

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Veröffentlicht in:	EMBO J
Hauptverfasser:	Schwab, Michael, Neutzner, Melanie, Möcker, Doreen, Seufert, Wolfgang
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Nature Publishing Group 2001
Schlagworte:	Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC125620/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11566880/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/20.18.5165
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