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The role of the –50 region of the human γ-globin gene in switching

During the switch from human γ- (fetal) to β- (adult) globin gene expression, the γ and β genes are expressed competitively by an alternating transcription mechanism. The –50 region of the γ gene promoter has been proposed to be responsible for the early competitive advantage of the γ genes and to a...

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Detalhes bibliográficos
Publicado no:EMBO J
Principais autores: Ristaldi, Maria Serafina, Drabek, Dubravka, Gribnau, Joost, Poddie, Daniela, Yannoutsous, Nikos, Cao, Antonio, Grosveld, Frank, Imam, A.M.Ali
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC125618/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11566887/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/20.18.5242
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