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Iron dysregulation combined with aging prevents sepsis-induced apoptosis
BACKGROUND: Sepsis, iron loading and aging cause independent increases in gut epithelial and splenic apoptosis. It is unknown how their combination will affect apoptosis and systemic cytokine levels. METHODS: Hfe(−/−) mice (a murine homolog of hemochromatosis) abnormally accumulate iron in their tis...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1255961/ https://ncbi.nlm.nih.gov/pubmed/15921699 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jss.2005.03.022 |
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