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Temporally coordinated assembly and disassembly of replication factories in the absence of DNA synthesis
Here we show that exposure of aphidicolin-arrested Chinese hamster ovary (CHO) cells to the protein-kinase inhibitors 2-aminopurine or caffeine results in initiation of replication at successively later-replicating chromosomal domains, loss of the capacity to synthesize DNA at earlier-replicating si...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2000
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1255923/ https://ncbi.nlm.nih.gov/pubmed/11025658 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/35036309 |
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