A direct interaction between JNK1 and CrkII is critical for Rac1-induced JNK activation
CrkII, a cellular homolog of v-crk, belongs to a family of adaptor proteins that play a central role in signal transduction cascades. We demonstrate that CrkII interacts directly with c-Jun N-terminal kinase 1 (JNK1). A proline-rich sequence of JNK1 is critical for the interaction of the kinase with...
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| Udgivet i: | EMBO J |
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| Principais autores: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2001
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC125507/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11432831/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/20.13.3437 |
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