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A direct interaction between JNK1 and CrkII is critical for Rac1-induced JNK activation

CrkII, a cellular homolog of v-crk, belongs to a family of adaptor proteins that play a central role in signal transduction cascades. We demonstrate that CrkII interacts directly with c-Jun N-terminal kinase 1 (JNK1). A proline-rich sequence of JNK1 is critical for the interaction of the kinase with...

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Bibliografske podrobnosti
izdano v:EMBO J
Principais autores: Girardin, Stephen E., Yaniv, Moshe
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2001
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC125507/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11432831/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/20.13.3437
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