Mixed lineage kinase-dependent JNK activation is governed by interactions of scaffold protein JIP with MAPK module components

It has been proposed that JNK-interacting proteins (JIP) facilitate mixed lineage kinase-dependent signal transduction to JNK by aggregating the three components of a JNK module. A new model for the assembly and regulation of these modules is proposed based on several observations. First, artificial...

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Pubblicato in:	EMBO J
Autori principali:	Nihalani, Deepak, Meyer, Debra, Pajni, Sangeeta, Holzman, Lawrence B.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Nature Publishing Group 2001
Soggetti:	Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC125504/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11432832/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/20.13.3447
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