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Mixed lineage kinase-dependent JNK activation is governed by interactions of scaffold protein JIP with MAPK module components

It has been proposed that JNK-interacting proteins (JIP) facilitate mixed lineage kinase-dependent signal transduction to JNK by aggregating the three components of a JNK module. A new model for the assembly and regulation of these modules is proposed based on several observations. First, artificial...

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Autori principali: Nihalani, Deepak, Meyer, Debra, Pajni, Sangeeta, Holzman, Lawrence B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2001
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC125504/
https://ncbi.nlm.nih.gov/pubmed/11432832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.13.3447
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