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Human immunodeficiency virus type 1 integrase: arrangement of protein domains in active cDNA complexes

Early steps of retroviral replication involve reverse transcription of the viral RNA genome and integration of the resulting cDNA copy into a chromosome of the host cell. The viral-encoded integrase protein carries out the initial DNA breaking and joining reactions that mediate integration. The orga...

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Autori principali: Gao, Kui, Butler, Scott L., Bushman, Frederic
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2001
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC125503/
https://ncbi.nlm.nih.gov/pubmed/11432843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.13.3565
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