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The death substrate Gas2 binds m-calpain and increases susceptibility to p53-dependent apoptosis
Gas2 is a caspase-3 substrate that plays a role in regulating microfilament and cell shape changes during apoptosis. Here we provide evidence that overexpression of Gas2 efficiently increases cell susceptibility to apoptosis following UV irradiation, etoposide and methyl methanesulfonate treatments,...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2001
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC125501/ https://ncbi.nlm.nih.gov/pubmed/11387205 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.11.2702 |
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