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A subcomplex of three eIF3 subunits binds eIF1 and eIF5 and stimulates ribosome binding of mRNA and tRNA(i)(Met)

Yeast translation initiation factor 3 contains five core subunits (known as TIF32, PRT1, NIP1, TIF34 and TIF35) and a less tightly associated component known as HCR1. We found that a stable subcomplex of His(8)-PRT1, NIP1 and TIF32 (PN2 subcomplex) could be affinity purified from a strain overexpres...

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Udgivet i:EMBO J
Principais autores: Phan, Lon, Schoenfeld, Lori W., Valášek, Leoš, Nielsen, Klaus H., Hinnebusch, Alan G.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2001
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Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC125478/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11387228/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/20.11.2954
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