Evolutionarily divergent electron donor proteins interact with P450MT2 through the same helical domain but different contact points

We have investigated the sites of N-terminally truncated cytochrome P4501A1 targeted to mitochondria (P450MT2) which interact with adrenodoxin (Adx), cytochrome P450 reductase (CPR) and bacterial flavodoxin (Fln). The binding site was mapped by a combination of in vitro mutagenesis, in vivo screenin...

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Bibliographic Details
Main Authors: Anandatheerthavarada, Hindupur K., Amuthan, Govindasamy, Biswas, Gopa, Robin, Marie-Anne, Murali, Ramachandran, Waterman, Michael R., Avadhani, Narayan G.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2001
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC125462/
https://ncbi.nlm.nih.gov/pubmed/11350928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.10.2394
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