Chemokine receptor homo- or heterodimerization activates distinct signaling pathways

Chemokine receptors of both the CC and CXC families have been demonstrated to undergo a ligand-mediated homodimerization process required for Ca(2+) flux and chemotaxis. We show that, in the chemokine response, heterodimerization is also permitted between given receptor pairs, specifically between C...

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Main Authors: Mellado, Mario, Rodríguez-Frade, José Miguel, Vila-Coro, Antonio J., Fernández, Silvia, Martín de Ana, Ana, Jones, David R., Torán, José L., Martínez-A, Carlos
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2001
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC125458/
https://ncbi.nlm.nih.gov/pubmed/11350939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.10.2497
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