The structural basis of acyl coenzyme A-dependent regulation of the transcription factor FadR
FadR is an acyl-CoA-responsive transcription factor, regulating fatty acid biosynthetic and degradation genes in Escherichia coli. The apo-protein binds DNA as a homodimer, an interaction that is disrupted by binding of acyl-CoA. The recently described structure of apo-FadR shows a DNA binding domai...
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| Publicado no: | EMBO J |
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| Principais autores: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC125426/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11296236/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/20.8.2041 |
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