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A family of Rhomboiproteases activates all Drosod intramembrane phila membrane-tethered EGF ligands
Drosophila has three membrane-tethered epidermal growth factor (EGF)-like proteins: Spitz, Gurken and Keren. Spitz and Gurken have been genetically confirmed to activate the EGF receptor, but Keren is uncharacterized. Spitz is activated by regulated intracellular translocation and cleavage by the tr...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC125406/ https://ncbi.nlm.nih.gov/pubmed/12169630 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdf434 |
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