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Physiological and retinoid-induced proliferations of epidermis basal keratinocytes are differently controlled

To investigate the roles of retinoic acid (RA) receptors (RARs) in the physiology of epidermis that does not express RARβ, conditional spatio-temporally controlled somatic mutagenesis was used to selectively ablate RARα in keratinocytes of RARγ-null mice. Keratinocyte proliferation was maintained in...

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Bibliographic Details
Published in:EMBO J
Main Authors: Chapellier, Benoit, Mark, Manuel, Messaddeq, Nadia, Calléja, Cécile, Warot, Xavier, Brocard, Jacques, Gérard, Christelle, Li, Mei, Metzger, Daniel, Ghyselinck, Norbert B., Chambon, Pierre
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2002
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Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC125394/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12093741/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdf331
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