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CLAC: a novel Alzheimer amyloid plaque component derived from a transmembrane precursor, CLAC-P/collagen type XXV
We raised monoclonal antibodies against senile plaque (SP) amyloid and obtained a clone 9D2, which labeled amyloid fibrils in SPs and reacted with ∼50/100 kDa polypeptides in Alzheimer’s disease (AD) brains. We purified the 9D2 antigens and cloned a cDNA encoding its precursor, which was a novel typ...
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| 主要な著者: | , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
2002
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC125364/ https://ncbi.nlm.nih.gov/pubmed/11927537 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/21.7.1524 |
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