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Human skin cells support thymus-independent T cell development

Thymic tissue has previously been considered a requirement for the generation of a functional and diverse population of human T cells. We report that fibroblasts and keratinocytes from human skin arrayed on a synthetic 3-dimensional matrix support the development of functional human T cells from hem...

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Autors principals: Clark, Rachael A., Yamanaka, Kei-ichi, Bai, Mei, Dowgiert, Rebecca, Kupper, Thomas S.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1253623/
https://ncbi.nlm.nih.gov/pubmed/16224538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI24731
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