The centrosomal protein TACC3 is essential for hematopoietic stem cell function and genetically interfaces with p53-regulated apoptosis

TACC3 is a centrosomal/mitotic spindle-associated protein that is highly expressed in a cell cycle-dependent manner in hematopoietic lineage cells. During embryonic development, TACC3 is expressed in a variety of tissues in addition to the hematopoietic lineages. TACC3 deficiency causes an embryonic...

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Auteurs principaux: Piekorz, Roland P., Hoffmeyer, Angelika, Duntsch, Christopher D., McKay, Catriona, Nakajima, Hideaki, Sexl, Veronika, Snyder, Linda, Rehg, Jerold, Ihle, James N.
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2002
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC125348/
https://ncbi.nlm.nih.gov/pubmed/11847113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/21.4.653
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