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The distal region and receptor tyrosines of the Epo receptor are non-essential for in vivo erythropoiesis

The erythropoietin receptor (EpoR) is required for the proliferation and survival of committed erythroid lineage cells. Previous studies have utilized receptor mutations to show the requirement for the distal half of the cytoplasmic domain of the EpoR and receptor tyrosines for activation of signali...

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Autori principali: Zang, Heesuk, Sato, Ken, Nakajima, Hideaki, McKay, Catriona, Ney, Paul A., Ihle, James N.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2001
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC150206/
https://ncbi.nlm.nih.gov/pubmed/11406592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.12.3156
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