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The distal region and receptor tyrosines of the Epo receptor are non-essential for in vivo erythropoiesis

The erythropoietin receptor (EpoR) is required for the proliferation and survival of committed erythroid lineage cells. Previous studies have utilized receptor mutations to show the requirement for the distal half of the cytoplasmic domain of the EpoR and receptor tyrosines for activation of signali...

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Detalhes bibliográficos
Main Authors: Zang, Heesuk, Sato, Ken, Nakajima, Hideaki, McKay, Catriona, Ney, Paul A., Ihle, James N.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2001
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC150206/
https://ncbi.nlm.nih.gov/pubmed/11406592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.12.3156
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