Two distinct effects on neurotransmission in a temperature-sensitive SNAP-25 mutant

Vesicle fusion in eukaryotic cells is mediated by SNAREs (soluble N-ethylmaleimide-sensitive factor attachment protein receptors). In neurons, the t-SNARE SNAP-25 is essential for synaptic vesicle fusion but its exact role in this process is unknown. We have isolated a SNAP-25 temperature-sensitive...

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Main Authors: Rao, Sujata S., Stewart, Bryan A., Rivlin, Patricia K., Vilinsky, Ilya, Watson, Brendon O., Lang, Cynthia, Boulianne, Gabrielle, Salpeter, Miriam M., Deitcher, David L.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2001
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC125330/
https://ncbi.nlm.nih.gov/pubmed/11726512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.23.6761
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