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Functional anatomy of siRNAs for mediating efficient RNAi in Drosophila melanogaster embryo lysate
Duplexes of 21–23 nucleotide (nt) RNAs are the sequence-specific mediators of RNA interference (RNAi) and post-transcriptional gene silencing (PTGS). Synthetic, short interfering RNAs (siRNAs) were examined in Drosophila melanogaster embryo lysate for their requirements regarding length, structure,...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2001
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC125328/ https://ncbi.nlm.nih.gov/pubmed/11726523 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.23.6877 |
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