Mad2 binding to Mad1 and Cdc20, rather than oligomerization, is required for the spindle checkpoint

Mad2 is a key component of the spindle checkpoint, a device that controls the fidelity of chromosome segregation in mitosis. The ability of Mad2 to form oligomers in vitro has been correlated with its ability to block the cell cycle upon injection into Xenopus embryos. Here we show that Mad2 forms i...

Deskribapen osoa

Xehetasun bibliografikoak

Argitaratua izan da:	EMBO J
Egile Nagusiak:	Sironi, Lucia, Melixetian, Marina, Faretta, Mario, Prosperini, Elena, Helin, Kristian, Musacchio, Andrea
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	Nature Publishing Group 2001
Gaiak:	Article
Sarrera elektronikoa:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC125308/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11707408/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/20.22.6371
Etiketak:	Etiketa erantsi Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!