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Specificity of the HP1 chromo domain for the methylated N-terminus of histone H3

Recent studies show that heterochromatin-associated protein-1 (HP1) recognizes a ‘histone code’ involving methylated Lys9 (methyl-K9) in histone H3. Using in situ immunofluorescence, we demonstrate that methyl-K9 H3 and HP1 co-localize to the heterochromatic regions of Drosophila polytene chromosome...

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Udgivet i:EMBO J
Principais autores: Jacobs, Steven A., Taverna, Sean D., Zhang, Yinong, Briggs, Scott D., Li, Jinmei, Eissenberg, Joel C., Allis, C.David, Khorasanizadeh, Sepideh
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2001
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Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC125272/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11566886/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/20.18.5232
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