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Specificity of the HP1 chromo domain for the methylated N-terminus of histone H3

Recent studies show that heterochromatin-associated protein-1 (HP1) recognizes a ‘histone code’ involving methylated Lys9 (methyl-K9) in histone H3. Using in situ immunofluorescence, we demonstrate that methyl-K9 H3 and HP1 co-localize to the heterochromatic regions of Drosophila polytene chromosome...

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Detalhes bibliográficos
Main Authors: Jacobs, Steven A., Taverna, Sean D., Zhang, Yinong, Briggs, Scott D., Li, Jinmei, Eissenberg, Joel C., Allis, C.David, Khorasanizadeh, Sepideh
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2001
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC125272/
https://ncbi.nlm.nih.gov/pubmed/11566886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.18.5232
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