Separate SCF(CDC4) recognition elements target Cdc6 for proteolysis in S phase and mitosis
The Cdc6 DNA replication initiation factor is targeted for ubiquitin-mediated proteolysis by the E3 ubiquitin ligase SCF(CDC4) from the end of G(1) phase until mitosis in the budding yeast Saccharomyces cerevisiae. Here we describe a dominant-negative CDC6 mutant that, when overexpressed, arrests th...
保存先:
| 出版年: | EMBO J |
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| 主要な著者: | , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group
2001
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC125267/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11532947/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/20.17.4836 |
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