The Dictyostelium homologue of mammalian soluble adenylyl cyclase encodes a guanylyl cyclase

A new Dictyostelium discoideum cyclase gene was identified that encodes a protein (sGC) with 35% similarity to mammalian soluble adenylyl cyclase (sAC). Gene disruption of sGC has no effect on adenylyl cyclase activity and results in a >10-fold reduction in guanylyl cyclase activity. The scg– null m...

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Publié dans:	EMBO J
Auteurs principaux:	Roelofs, Jeroen, Meima, Marcel, Schaap, Pauline, Van Haastert, Peter J.M.
Format:	Artigo
Langue:	Inglês
Publié:	Nature Publishing Group 2001
Sujets:	Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC125260/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11500361/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/20.16.4341
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