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The Dictyostelium homologue of mammalian soluble adenylyl cyclase encodes a guanylyl cyclase

A new Dictyostelium discoideum cyclase gene was identified that encodes a protein (sGC) with 35% similarity to mammalian soluble adenylyl cyclase (sAC). Gene disruption of sGC has no effect on adenylyl cyclase activity and results in a >10-fold reduction in guanylyl cyclase activity. The scg– nul...

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Bibliographic Details
Main Authors: Roelofs, Jeroen, Meima, Marcel, Schaap, Pauline, Van Haastert, Peter J.M.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2001
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC125260/
https://ncbi.nlm.nih.gov/pubmed/11500361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.16.4341
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